queG [2017-8-11 16:0:3]

epoxyqueuosine reductase

locus: BSU08910

pI: 7.35

mw: 48.37 kDa

protein length: 435 aa

gene length: 1305 bp

function: synthesis of queuosine, tRNA modification

product: epoxyqueuosine reductase

essential: no

synonyms: ygaP, yhbA

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]

Gene

Coordinates: 967,935 → 969,095

The protein

Catalyzed reaction/ biological activity

• conversion of epoxyqueuosine to queuosine [Pubmed|21502530]

[SW|Cofactors]

• cobalamin, [4Fe-4S] cluster [Pubmed|21502530]

Structure

• [PDB|5D08] [Pubmed|27638883]

Expression and Regulation

Operons

• genes: [gene|3F22BD8DB7BEC2701B960546AC683603DFCADCCE|queG]
  description: [pubmed|22383849]

Biological materials

Mutant

• MGNA-A241 (yhbA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/241 NBRP B. subtilis, Japan]

References

• 26230193,21502530,27638883